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The finding, that in most cases, differences across population groups related to the relative strength of preference rather than different management preferences per se, suggests that the under-representation of some population groups in this study will not have affected materially the management preferences found.
Apart from these extreme cases, differences across EU countries, and notably countries of Continental Europe, may not be very large, as suggested by Evers et al. (2008).
In many cases, differences across trials do not result in meaningful discrepancies in pooled results, and an MTC should not be any more conservative in terms of inclusion criteria than any other meta-analysis.
Although four out of these five studies used the same procedures and definitions to obtain DR cases, differences across these studies in the distribution of age and other cardiovascular risk factors, sample sizes, and follow-up periods may partially explain this discrepancy.
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In the other two cases differences were randomly distributed across the region.
It noted that in some cases differences in definitions meant that the data were not always precisely compatible across countries.
STD surveillance data are subject to limitations, such as incomplete reporting of cases and differences across jurisdictions in how data are collected (13 ).
In this work we present mixed effects models to study clustering while simultaneously taking case-mix differences across physicians into account.
Case-mix differences across regions can lead to inaccurate perceptions of quality and risk adjustment is a method used to attempt to "level the playing field" across different regions [ 14].
Second, the difference between the global peak and accessible local peaks may be negligible, in which case differences in adaptive magnitude across populations of different sizes will be similarly small.
Case and control differences across baseline characteristics were assessed by paired t-tests (continuous variables) or by generalised McNemar's Test (categorical variables).
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