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Sample size: considering a rate of ADR-SM possibly not over 1%% of ED patients (personal data), we targeted the enrolment of approximately 5,000 patients (in order to observe a minimum of 30 cases, alpha risk 0.05, power >0.80).
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Asset managers search for alpha, risk adjusted outperformance relative to a benchmark.
For each test, the alpha risk was set at 0.05.
All tests were two-tailed assuming alpha risk = 0.05.
Logistic regression was used for multivariate analysis (alpha risk 0.05).
Alpha risk was 5%.
Since both hypotheses addressed different objectives, no adjustment of the alpha risk consumption was made.
For all tests, the bilateral alpha risk was α = 0.05.
Statistical tests were considered significant with a 5% alpha risk.
The variation of the alpha risk with residual correlation showed that the alpha risk increased when residual correlation decreased.
The use of this multiplicative coefficient controls the risk of wrongly concluding linkage (alpha risk).
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