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In no case was loss of Dsc2 message detected, suggesting that transcriptional mechanisms are not responsible for the loss of Dsc2 protein.
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The only copy number change seen in more than 60% of cases was loss of 17p13 (Additional file 1 and Figure 2A-a).
Apart from a near-diploid chromosome number, the only recurrent cytogenetic features among the four cases were loss of band 10q26 and rearrangements of 1p13 and 12q13, found in two cases each.
Of those that lost the same parental homoeolog, nine cases were losses of T. dubius, while two were losses of T. pratensis.
In Dr. F eller's case, there was loss of motion, atrophy and gangrene of toes.
LOH at the p73 locus was observed in 37.8% (14/37) of the AT/GC heterozygotes studied; in all cases there was loss of the AT allele.
At the heart of the case was the loss of $43m incurred through the purchase of ships without government approval and two failed power plant projects.
The alveolar bone defect in this case was the loss of ridge height with normal ridge width, class II according to the Seibert classification [20].
Importantly, in no case was the loss of HCV-specific CD4+ T cell function accompanied by a relevant decrease of recall antigen (tetanus toxoid) or mitogen (PHA) responses.
A notable indel case was the loss of an entire exon at the 5' end of the Clfb gene in comparison with Clfa (Additional file 6 -e.g. 1B).
The Pentagon Papers case was a total loss for the president: Ellsberg went free and the New York Times won a Pulitzer Prize.
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