In other cases, simplifications must be made in response to scarce data, incomplete knowledge, or restrictions set by the spatio-temporal scale of application.
Consequently, for the investigated case a simplification to a homogenous brick layer is allowed.
Whereas simplifications similar to (ii) and (iii) have also been applied to APP algorithms from literature (e.g., max-log MAP), this is not the case for simplification (i).
In any case, this simplification allowed us to verify that these classes of codons are not associated with portions of SLC2A4 upstream of exon 7 or downstream of intron 6.
In this case, the simplification of using the physical sampling window area (Aphys = 3.14 cm) and the simple DGT equation was found to be acceptable.
In this case, some simplifications on the general expressions derived above are possible.
Even concepts more complex than standard studies, such as pedocomplex and welded soils, are considered inside the theoretical basis that assumes that a soil (paleosol) is a unique, homogeneous, isolated sheet located on (or between) clearly different sediment strata or other geological bodies, which is in many cases a simplification.
In almost every case the simplifications reflected in this model would tend to underestimate the true cost-effectiveness of the vaccine.
Here, as detailed example of simplification process, a case study of a large multi-storey office building is modelled starting with a previous detailed simulation performed through EnergyPlus and Openstudio software.
Usually, authors focus on the proposed mechanisms and their performance, and, in some cases, relevant simplifications are made (e.g., ideal wireless channel conditions [15]).
