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One spectacular case of suppression involved the performance of Britain's Tony Blair at an event billed as the Clinton Global Initiative.
Similar observations were reported in the case of suppression of hepatic gluconeogenesis by TCDD through the AHR target gene TiPARP [TCDD-inducible poly(ADP-ribose) polymerase; Diani-Moore et al. 2010].
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In this analysis viral suppression was determined as treatment success in case of viraemic suppression to at least 500 copies/ml including any category of low-level viral load measurement (<400, <50 and <40 copies/ml).
The importance of the phase history of preceding stimuli was borne out, and was particularly marked in the case of tremor suppression; when stimulation happened to be applied at phase values favouring tremor suppression over five cycles, the mean effect across all suppressive phases was increased ∼threefold, from <10% to ∼30%.
The most famous case of scientific suppression remains that of Galileo, who in 1633 was forced by the Roman Catholic Church to disavow his finding that the Earth revolves around the Sun.
This intriguing case of bypass suppression suggests that Plk1 normally reduces the strength of the Mad2-dependent inhibitory SAC signal.
Thus, the observed restoration of SAC activity would represent a case of bypass suppression rather than genuine rescue.
We speculate that activation of stimulus-specific RBPs and miRs is a major factor that underlies the deviation from model's prediction in the case of gene suppression.
In the absence of interaction, the influence of humidity may represent a case of variance suppression (Tabachnick and Fidell 1985), whereby confounding variables may increase the effect size of the primary risk variable in the model.
Yet, increase of chromatographic resolution is a preferable way to reduce matrix effects because, in the case of ion suppression, signal intensity is improved [ 21], which will also positively affect precision of the measured isotope ratio.
In vivo, changes consequent to loss of PPARγ were associated with hyperplasia, PIN formation and progression to malignancy, which in the case of PPARγ2 suppression could be rescued using high levels of the PPARγ agonist Rosiglitazone.
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