Sentence examples for case of lethality from inspiring English sources
In case of lethality, larvae of the right genotype were identified by insc-Gal4-driven CD8::GFP (brand and salivary gland) using a fluorescence microscope.
The normal structure of thoracic viscera and their branches (data not shown) suggested that altered cardiovascular or pulmonary function a common etiology for perinatal mortality was also not the cause of lethality in this case.
trichostatin A. Pancreatic cancer is the second leading cause of lethality in the cancer-associated cases of the digestive system.
In the case of lethal strains, the developmental stage at which lethality occurs was determined by genotyping of embryos at E14.5 and E18.5 and newborns.
The authors did not suspect that they were observing a case of synthetic lethality.
In the case of low lethality of mutants, it was shown that there is no error-threshold in a multiplicative fitness landscape.
Although no inherited diseases are known to result from mutation of these genes, one case of neonatal lethality has been attributed to a defect in Drp1 (25).
Additionally, genetic interactions between genes are rare but they have a detectible impact on phenotype, with a wide range of dosage effects from causing only a few per cent change in growth phenotype to the extreme case of synthetic lethality (see the section below on Gene Interactions) (specify section number).
The absence or dysfunction of essential proteins would create an adverse disruption to the topological stability of the network as in the case of PIN biological lethality.
In case of chemotherapy, synthetic lethality could emerge, increasing tumour control by the treatment and thereby improving patient survival, a similar synthetic lethal effect as observed for BRCA1-deficient breast tumours treated with PARP inhibitors [ 11, 13, 38].
In the case of antibiotics, synthetic lethality provides a basis for why this would be the case, and analogous effects may be at work in the case of anticancer drugs believed to act on multiple signaling proteins, such as imatinib and sunitinib.
