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In the case of GAIN, Founder and CEO Nick Gammell said that, initially, the teams' focus was solely on the Web.
In the case of gain control mediated by an interneuron this can be achieved in a number of ways, for example, through facilitating inhibitory synaptic transmission (Silver, 2010; Figure 9).
We therefore conclude that SNORA58 has moved into genes traceable to LECA, and that, in the case of MRPL3, this is an irrefutable case of gain of both intron and intronic snoRNA.
Selected UN agencies (in the case of GAIN only one UN or other multilateral agency) that have mandates to deal with these health matters are invited to join their boards either as voting (GAVI and GAIN) or non-voting (GFATM) members, while industry and other private sector actors are included as full members at all levels of their structures [ 2, 6].
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In the case of gain-of-resistance mutants, several studies have provided useful insights into the regulation of defense (Feys and Parker 2000; Frye and Innes 1998; Yu et al. 2000; Thatcher et al. 2005).
Władysław promised not to sign any pacts against the Habsburgs, and to transfer his rights to the Swedish throne in case of his line's extinction; in return, Habsburg promised to support his efforts to regain the Swedish crown, and to transfer to him some territory in case of gains in a war against the Ottomans.
The same argument applies in the case of gains and a negative location bias.
In case of gain-of-function URAT1 polymorphism, 1 was assigned to those with the reference allele, 2 to heterozygotes, and 3 to those homozygous for the gain-of-function allele.
Of the 91 patients with both aCGH and FISH results, aCGH detected 11.0% (10/91) of CNAs that were not detected by FISH [6 cases of del(13)(q14), 2 cases of del(17)(p13), and 2 cases of gain(1)(q21)].
On the contrary, I-FISH detected 11% (10/91) of abnormalities not identified by aCGH [2 cases of del(13)(q14), 3 cases of del(17)(p13), and 5 cases of gain(1)(q21), resp.].
However, if intron gain was, indeed, episodic in eukaryotic in eukaryotes as suggested in this paper and previously elsewhere (ref. 50), such unequivocal cases of gain are likely to be very few and far between, and this seems to be so.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com