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These last sequences were systematically realised, to better define boundaries of necrosis, especially in case of extra prostatic necrosis.
The EEC Regulation 2568/91 does not give any indication on the way to report the uncertainty of the results, and in the case of extra virgin olive oils with a borderline value, the way to report the fatty acid ethyl ester content, with or without the uncertainty, can create confusion in defining the olive oil quality grade.
Off-target activities are not unusual in compound development, and in the case of extra biological effects upon antigen presentation and cytokine function, could even be beneficial.
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The same guideline was applied in case of extra-haematological toxicity (excluding alopecia, nausea and vomiting) to allow recovery to a grade ⩽1.
This one-cell case of extra-cellular positive feedback shows similar bistability as in the case of intracellular non-linear positive feedback.
To our knowledge, this is the first case of extra-pancreatic insulin secreting neuroendocrine tumour fully characterised by biochemical, radiological & functional imaging, histopathology and immunohistochemistry.
The confirmed post randomization HIV disease progression events observed in this trial were: five cases of extra pulmonary tuberculosis (all in the placebo arm), and one case of Kaposi sarcoma in the intervention arm.
In the Netherlands, the annual incidence of pancreatic cancer is around 1700 new cases of pancreatic cancer and around 440 cases of extra hepatic bile duct cancer (source: Netherlands Cancer Registry).
The first line drugs used for pregnant women in the studies included INH, ethambutol (ETB), rifampicin (RIF), and, in some cases of extra pulmonary TB, pyrazinamid (PZA) [ 15, 19, 33, 45].
The main reasons for this delay are that women seek health services and prenatal care at a late stage of their pregnancy and that TB during pregnancy is asymptomatic or has nonspecific symptoms, especially in cases of extra pulmonary TB [ 18, 23, 38, 45].
The case notification of extra pulmonary tuberculosis is in Ethiopia is also higher and almost equal to that of smear positive and negative pulmonary tuberculosis cases with a percentage of 33 each [ 8].
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