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In this case loci reaching suggestive significance will be followed-up in a confirmatory screen that utilises F2 mice.
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These identifications are noted in Table S2A upper case locus and gene names denote genes previously identified according to SGD (accessed August 2010), while lower case locus and gene names denote those newly identified by our screen.
In one extreme case, locus Dpul_327924, six different, derived introns were identified in close proximity in alignments of one exon (fig. 4 and supplementary fig. S58 a g, Supplementary Material online).
In this method, IBD probabilities are calculated for a fictitious locus A in the middle of a marker interval, where information is used from the markers on either side of this locus A. In our case, locus A is positioned at the marker locus in the middle of each marker interval.
As the sequences were obtained from multiple individuals, it is not possible to confidently distinguish between alternative isoforms, alleles and in some cases, loci.
In most cases, locus information was available or could be inferred.
In our case, these loci were defined as Cross Pollinator (CP -type loCP -typee software JoinMap (Kyazma B.V., Wageningen, Nloci
Such a structure refers to the case that loci have the same genotype when restricted to these progeny strains.
An explicit formula for T can be derived in the extreme case where loci have identical allele frequencies.
In this latter case, rDNA loci inherited from both parents are conserved but rDNA genes derived from one progenitor are silent (Lewis et al. 2007; Pikaard 2000).
In this case even loci with small numbers of clustered reads showed significant enrichment with respect to the Bmp2k control (Fig. 2C).
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