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Our reconstruction of an evolutionary relationship between viruses provides precise information about case linkages.
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In this case, linkage studies would not the method of choice for detection.
For speciation to occur in such a case, linkage between mate and resource preferences must be maintained in sympatry to uphold the genetic integrity of the diverging populations [15].
Once individual case linkage is established, all reimbursed healthcare intervention can be retrieved from the AGIS database.
If this is the case, linkage of MIR169 copies to either bHLH or COL genes could have been preserved even after the monocotyledonous diversification.
The absence of case linkage between the two data sources prevents exact correlation between them; however, the number of domestic cases from the isolate collection is approximately 40% of the number of cases in NIDR for the same period.
In case linkage for the second round had not been done by the end of 2007 (those in the first round in 2006), the follow-up ended on 31 December 2007 (at the end of follow-up for cancer).
In case linkage was observed, or at least suggested, a replication test was planned with the TDT RA sample 2 and a global analysis for all TDT RA families.
In this case, linkage analysis and homozygosity mapping can be performed by analyzing subgroups of the affected individuals, by comparison of the observed maximum LOD score with the MLOD/EMLOD score for the pedigree subgroup and, when appropriate, identification of those affected individuals who share the same homozygous region.
In other cases, linkages between environmental agents, individually or as mixtures, and health outcomes lack epidemiologic evidence and are postulated from laboratory animal studies.
In both cases, linkage equilibrium between markers was assumed.
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