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It doesn't mean each case is a problem.
"The Moussaoui case is a problem," he said.
The Searson case is a problem for Pell: he investigated the priest and left him in his Melbourne parish.
But the case is a problem for not only Comodo, which initially believed the attack was the work of the Iranian government.
Hence, a case is a problem with its solution and cases are stored in a case library.
Hence, the instability of the drugs (or benzodiazepines and opiates in this case) in different biological samples (or urine in this case) is a problem of data interpretation in analytical toxicology.
Similar(54)
In general, determination of eigenvalues and eigenfunctions, except for a few cases, is a problem that is very involved, if not impossible.
Those on both sides of the debate agree that a lack of state data on automatic transfer cases is a problem.
Despite the high profile the investigation was attracting, there was evidence that the huge weight of cases was a problem for the authorities.
These CNS adverse events of triptans, especially sleepiness/tiredness, can in some cases be a problem in the clinical use of the drugs, including sumatriptan [3].
The generalization of those results to the non-radial case is a challenging open problem.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com