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In this case immune genes should be evenly spread out across the genome and clustering should be minimal.
In either case, immune factors are central.
In that case, immune response should be characterized by lower lymphocytes and neutrophils counts in the basal state but an increased inflammatory response resolving rapidly during the postoperative phase.
In this case, immune cells can be imaged in vivo before and during the generation of the attractive signal, allowing the monitoring of cell behavior during the key transition between random walk and chemotaxis.
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In many cases immune deficiencies (defect in cellular immunity, monocyte deactivation) closely resemble those observed in patients after 'non-neurological' trauma, surgical injury, or blood loss [ 10].
In some cases immune deficiencies result from damage inflicted by infectious agents.
In these cases, immune components induced by one antigen are able to react with all other antigens carrying the same epitope.
In some cases, immune priming can even be trans-generational, as observed for the mealworm beetle Tenebrio molitor[ 55].
Even among the triple-negative cases, immune response has different meanings in core basal versus 'five negative' phenotypes.
The most common other HPO terms described abnormalities of the nervous system (149 index cases), immune system (107 index cases) and skeletal system (102 index cases).
C3 deficiencies are extremely infrequent, but patients usually suffer from repeated infections, and in some cases, immune complexes-related disorders are reported [ 3, 6, 7].
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