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We have also investigated the receptor binding affinity and the ability of these analogs to stimulate intracellular signaling pathways, although in our case by measuring phosphorylation of ERK1/2.
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The authors then examined the levels of circulating PGE2, PGD2, PGF2α, PGI2 and thromboxane A2 [TXA2] — in most cases by measuring their stable metabolites as surrogates.
Residual β-cell function was assessed at the initial visit at the clinics in prevalent cases or at disease stabilization in incident cases, by measuring fasting plasma C-peptide (normal values 0.36 1.17 nmol/l; Diagnostics Product Corporation, Los Angeles, CA).
Hyperhomocysteinemia should be considered and tested (in most cases by measuring plasma homocysteine levels) as another potential risk factor in those found to be positive for factor V Leiden.
The incorporation of deuterium into each peptide was computed for most cases by measuring the average mass of the isotopic clusters over the full m/ z range for the peptide as follows.
The concentration of this quantitation standard is, in most cases, determined by measuring UV absorbance.
The degree of purity of these fractions was analyzed by morphology and/or morphometry and in many cases biochemically by measuring the level of enrichment of expected proteins (markers) compared to the starting material (Table 1).
Throughput in the coded case is evaluated by measuring the BER by computer simulation.
In this case, results were obtained by measuring UDP-GlcUA consumption on HPLC or CE.
In both cases, spin is obtained by measuring the inner radius of the accretion disk, which corresponds to the innermost stable circular orbit ISCO.
The paper also reports on the experience gained in two external trial cases and results obtained by measuring the tractability of the implementation of the proposed validation approach.
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