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In this case, array elements are grouped in two clusters (of the same size) that are located at different distances from the main receiver.
Since unexpressed genes or genes expressed below the detection limit of the technique (in this case array) will appear to be dosage compensated, we excluded all genes not expressed in males and/or females, using the same approach as in previous studies [ 18, 25, 26].
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In the present case, arrays of microvias were drilled on silica and borosilicate glass specimens using laser radiation with a repetition of 8 MHz and pulse width 214 fs.
In these cases array probes were mapped based on their sequence using the Exonerate program (23).
Lastly, when comparing clinical sporadic MTC tumors with hereditary cases, array studies revealed an almost universal elevation in autophagy-related genes in SMTC.
In complex cases, array comparative genomic hybridisation (CGH) or single-nucleotide polymorphism (SNP)/copy number variant (CNV) analysis may also be performed looking for submicroscopic deletions or duplications that might be relevant.
It has to be pointed out that in the previous two cases array CGH analyses were carried out in the parents after extensive review of the publicly available databases (DGV, DECIPHER) as well as our own dataset.
At the grand tourism office on the corner of the square, I scooped up every brochure I could while my consort browsed the display cases arrayed with Nancy souvenirs and investments, from hard candies in elaborate turn-of-the-century tins to Art Nouvasesinspired vandscarvescarves priced higher than our hotel room.
Mr. Zardari had never been convicted, despite having spent 11 years in jail, proof they say that the cases arrayed against him are political vendettas without substance and aimed at undermining the civilian government's current agenda, which is pro-American, in the face of a resurgent military.
In some cases, arrays are simply disorganized (Bichet et al. 2001; Whittington et al. 2001; Burk and Ye 2002; Webb et al. 2002; Bouquin et al., 2003).
In all cases array-positive interactions were of high affinity (range 0.18 μm – 5.8 μM, median KD = 2 μM), while array negative interactions were demonstrably lower affinity (median KD > 30 μM).
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