Also, within statutory code sections, the navigation links provided within the case annotation index routinely loaded an error page rather than navigating to the proper section further down the page.
In any case, annotation databases for non-coding elements are still in their infancy.
In case, annotation information is unavailable from these three databases, then information from TrEMBL or GenBank Viridiplantae Nucleotide database annotations was used.
A highly effective informatics infrastructure has been designed for the resource that facilitates an efficient governance, standardized data acquisition, and thoroughly standardized case annotation across multiple participating sites.
In this case, annotation may continue to be provided by one or both annotation groups; however, the annotation is not considered sufficiently supported to be retained in the CCDS database.
For each case, a knowledge engineer (MC) and an expert dermatopathologist (DJ) collaborated in defining all present findings and locations (case annotation) and in developing the relationships among findings and diagnoses (knowledge base development).
Of note, interested investigators were encouraged to submit a full application describing their research protocol and tissue request without having reviewed the detailed case annotation, thus eliminating the possibility of case selection bias.
In this case, annotation terms are integrated into the data and do not appear as complete source vocabularies or as subsets of the UMLS that would be suitable as a medical vocabulary.
Fisher's exact test was used to annotate each cluster with significant enrichments for a variety of external gene sets (Additional files 1 and 2); in each case, annotation significance was determined by Benjamini-Hochberg false discovery rate (FDR) correction for multiple hypothesis testing over all clusters.
In some cases, annotations are also added to the parameters and mathematical expressions.
