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The leukocyte adhesion cascade inside blood vessels includes rolling, adhesion, and crawling1,2,3,4.
This pleiotropy of GPCRs is enabled by their structural flexibility manifested in thermally accessible multiple conformations, each of which may be capable of activating a different signaling cascade inside the cell (Kenakin & Miller, 2010).
This may indicate that the Au-NPs are interacting with the cathepsins indirectly, possibly through a signaling cascade, inside of the cells.
They added the modified adrenaline compound, called CP-331679, to cultured human fat cells, and saw that the receptors were activated and were triggering a biochemical cascade inside the cell.
Biomedical scientist Min Zhao of the University of Aberdeen in the United Kingdom and colleagues charged at the problem by creating a set of fluorescent markers that lit up when electrical signals set off a biochemical cascade inside the cell.
Upon engagement of the TCR, a signaling cascade inside the cell is initiated that leads to activation of the T cell.
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Originally, Mr. Arad called for no cultural buildings on the memorial site, which he envisioned at street level except for two 30-foot depressions, with pools and water cascades inside, marking the areas once occupied by the twin towers.
The environmental and flow induced signals regulate EC phenotype through activation of signaling cascades inside ECs.
Instead of a bottom-up insurgency by aggrieved elements of "society" against "the state", the rapidity and depth of the insurgency is the product of a cascading "inside-out" rebellions by China's own elites, motivated not by grievances against the status quo but by strategies to avoid becoming implicated in a rapidly escalating and unpredictable party purge.
As they rushed to the mosque, the fighting cascaded inside.
THE tiny soldiers that are the stars of Burlington Toys, a subterranean store at 1082 Madison Avenue, survived intact, but the Pee-wee Herman doll was put in harm's way recently when a boiler burst and hot water cascaded inside.
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