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Bursting emerges from tonic spiking through the spike-addition cascade in two different ways: one is regular and reversible; the corresponding transitions are foliated by the bifurcation curves.
We tested activation of ATM-dependent checkpoint signaling cascade in two iPS cell lines by Western blot (Figure 2A, Figure S1A) and immunocytochemistry (Figure 2B and 2C) after γ-irradiation.
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We have investigated the role of DPC4 in the TGF-beta receptor-mediated signal transduction cascade in five human pancreatic cancer cell lines (Panc-1, MDAPanc-28, HS766T, Capan-1, and MiaPaCa-2).
As one may expect, although the numbers of cascades in two datasets are similar, we will see that the running time of a network inference algorithm on these two datasets is very different.
Protection from the rise in ROS that accompanies such cytochrome c release could be mediated by survival kinase cascades in two ways.
We explored a model containing two polarized species in a cascade resulting in two amplification stages.
At least 80 feet high, the stream cascades in six steps along a precipice that was tough to climb until last fall, when the state cleared a trail and built a stairway of pressure-treated timber.
Although the leading causes of MDR phenotype are quite different, the PI3K/AKT signaling cascade in these two MDR cell lines was found to be overactivated compared with their parental cell lines.
DOI: http://dx.doi.org/10.7554/eLife.03031.018 HBI1 was recently identified as part of a tripartite HLH/bHLH cascade, in which two non-DNA binding HLH factors, PRE1 and IBH1, antagonize each other, and IBH1 interacts with HBI1 and inhibits HBI1 DNA-binding (Bai et al., 2012a).
> -wrap-foot> The yeast mating pathway contains a mitogen-activated protein kinase (MAPK) cascade in which three components (Fus3, Ste7, and Ste5) are downregulated in low-Hsp90 cells.
The roof of this home appears to cascade down in four layers of rock.
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