Sentence examples for cascade contributing from inspiring English sources

Thus, sustained GSK3 β activity represses a critical regulatory step in the myogenic cascade, contributing to the undifferentiated, proliferative phenotype in alveolar rhabdomyosarcoma (ARMS).

In both pathways, the constant cross talk between ubiquitylation (of various kinds) and phosphorylation fine-tunes the signal cascade contributing to NF-κB NF-κBactivation

Immune complexes become deposited in capillaries and in kidney glomeruli with inhibition of the complement cascade contributing to SLE susceptibility (Walport, 2002 for review).

The prooxidant effects of NP result in the activation of signaling pathways, transcription factors, and cytokine cascade contributing to a diverse range of cellular responses.

With this mechanism, the cells strive maybe to counterbalance the abnormal activation of the KLK proteolytic cascade contributing to their homeostasis.

Prostaglandins and their derivatives are endogenous autacoids produced by cyclooxygenase-related arachidonic acid cascade, contributing to vasodilatation [ 14], inhibition of platelet aggregation or anti-inflammation [ 15] in response against local tissue damage.

Activation of the hypothalamus-pituitary-adrenal (HPA) axis, resulting in a systemic rise in glucocorticoids and an acute systemic pro-inflammatory cytokine cascade, contributes to acute thymic involution [4].

In human thyroid carcinomas, constitutive signaling of the MAP kinase cascade contributes to the development of thyroid cancer promoted by activated RAS and BRAF onco-proteins and that this occurs, at least in part, by compromising the Skp2-dependent degradation pathway [30].

Or, in other words, does the mTOR/S6K cascade contribute to p66 effects on mouse lifespan?

This inflammatory cascade contributes to a systemic syndrome of weight loss, diarrhea, skin changes and high mortality.

Recent studies have reported that genetic lesions and overexpression of oncoproteins in TGF- β/Smads signalling cascade contribute to the TGF- β resistance.