Sentence examples for cascade constitutes from inspiring English sources

Iran's ability to accelerate this cascade constitutes an accelerated and inexorable march toward the development of weapons grade enriched uranium.

In the case of endometrial cancer cells, the PI3K/AKT/mTOR signal transduction cascade constitutes one of the main activation pathways of tyrosine kinase receptors such as vascular endothelial growth factor receptor 1 (VEGFR-1), platelet-derived growth factor receptor (PDGFR- α), epidermal growth factor receptor 1 (EGFR-1), and c-MET [ 31].

The most widely studied is the canonical signaling cascade constituted by PI3K/Akt, that controls glucose uptake, metabolic activity, and translational responses to insulin [ 37].

Antiphospholipid antibodies that interfere with phospholipid-dependent steps in the coagulation cascade constitute the lupus anticoagulant (LAC) determined by functional clotting tests.

Thus, the Sxl -regulated expression of fne fits within the context of Sxl acting in parallel with the canonical Sxl-tra/tra2 cascade, constituting an example of its impact on tissues that do not show obvious sexual dimorphism.

MAPKKKs (also named as MAP3Ks and MEKKs), known as the first step of MAPK cascade, constitute a diverse family of kinases which have been grouped into three large subfamilies based on the sequence of the kinase catalytic domain: the MEKK-like family, Raf-like fandly and ZIK-like family.

The Cascades constitute a climatic barrier to the prevailing moist weather systems moving eastward from the Pacific Ocean.

These results demonstrated that the MAPK and Ca2+ signalling may be mediated by R genes following Colletotrichum infection, and MAPK cascades constitute the main defence signalling pathway.

According to Katoh's summary, Wnt, FGF, Notch, SHH and TGFβ/BMP signaling cascades constitute the stem-cell signaling network, playing a key role in the maintenance or homeostasis of cancer stem cells (Katoh, 2011).

The activated Raf in the latter option phosphorylates the mitogen-activated protein kinase (MAPK) cascade, which constitutes the third module.

Caspase-8 activates other caspases by cleavage and this starts a proteolytic cascade which constitutes the "point of no return" in apoptotic signaling.