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We find that the AbdB-Boss/Sev cascade affects integrin independent of Talin, while genetic interactions depict integrin as the central downstream player in this system.
This study was designed to determine if disruption of the complement cascade affects RGC survival in a murine model of retinal ischemia-reperfusion (I/R) injury.
In this section we explore how some topological features of the train of spreaders involved in a cascade affects its final size.
Mutation of a signaling protease required for PPAF activation in the melanization cascade affects resistance and tolerance of infections in Drosophila [38].
Activation of the MAPK cascade affects processes such as cell proliferation, apoptosis, differentiation, and inflammation [ 7, 8].
PKI 14-22 was in the MeA of C57Bl/6 mice prior to social learning to determine whether blockade of the PKA/CREB/pCREB cascade affects social recognition.
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(D) Example of a global cascade affecting about 35,000 nodes.
While all of the mechanisms of incarceration affect the individual who is currently or formerly incarcerated, many also cascade, affecting families and communities.
Moreover, some factors in the GA signaling cascade affect flower development, particularly anther formation in rice (Kaneko et al. 2004; Chhun et al. 2007; Aya et al. 2009).
Upon receptor oligomerization, the type I receptor is phosphorylated at its intracellular glycine-serine-rich domain (the so-called GS box) by the constitutively active type II receptor kinase thereby activating the SMAD signalling cascade affecting transcription of responsive genes in the nucleus [6].
Additionally, arachidonic acid products may be involved in an inflammatory cascade, affecting cell survival.
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