Sentence examples for carrying mutant from inspiring English sources
Kurt, M. A. et al. Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes.
To investigate which of Glo's two RNA-binding modes was required for its different functions in flies, Gavis and colleagues generated insects carrying mutant versions of the RNA-binding protein.
These results suggest that the cell types targeted in vivo by VRP carrying mutant or wild type glycoprotein spikes are functionally different, and are consistent with previous findings suggesting that wild-type VEE glycoproteins preferentially target professional antigen presenting cells that use peptides generated from the degraded antigen for direct presentation on MHC.
And the battle may play out very differently in a developing embryo carrying mutant DNA than it did in these dishes of repeatedly cultured cell lines with only healthy DNA, experts warn.
Plasmids carrying mutant receptors CCR5STA and CCR5Δ4 were generous gifts from Dr. Murphy's group at NIAID, NIH.
For example, prolonged light exposure accelerated photoreceptor degeneration in transgenic mice carrying mutant forms of rhodopsin and in mice lacking rhodopsin kinase or arrestin.
Libraries of mutagenised constructs were transformed into yeast and the large normal phenotype colonies (carrying mutants that disrupt the BRCT domains) were isolated and sequenced to identify residues that disrupt the BRCT function (Figure 4a).
Relative mRNA expression ratios of the stably transfected plasmids did not differ between RKO cells carrying wild-type (or ancestral) allele and those carrying mutant-type (minor) allele (14.44±4.25 vs 13.49±2.78 for LIFR rs3729740, P=0.868; 2.64±0.07 vs 2.4±0.07 for ANXA11 rs1049550, P=0.133) after treatment with cetuximab and bevacizumab regimens, respectively.
QuikChange® Site-Directed Mutagenesis Kit (Stratagene) was used according to the manufacturer's instructions to generate C-terminal merlin point mutation carrying mutants Q324L, K413E and L535P.
They repeated many of the same experiments that had been conducted in the previous mouse models, which carried mutant versions of ankyrin-B throughout their bodies.
Researchers remove the nuclear DNA which accounts for the vast majority of the genetic information from an unfertilized egg cell that carries mutant mitochondria.
