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The model satellite will carry a modified Michel-son-type interferometer, for studying radiation reflected from the earth's surface.
Successful retargeting of herpes simplex virus type 1 (HSV-1) has been achieved using vectors that carry a modified envelope glycoprotein D (gD) engineered to interact directly with novel receptors.
Additionally, pCS2TAL3-RRR/DDD vectors carry a modified nuclease domain that renders the homodimeric FokI an obligate heterodimer.
Hapten-positioned disulfide-connected payloads can be delivered to and into cells by bispecific cell-targeting antibodies (bsAbs) that carry a modified hapten binding entity as second specificity.
In the meantime, big tobacco companies are developing alternative nicotine products they hope one day will carry a "modified risk" of harm.
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Preproinsulin for PIns was cloned and expressed using a bacterial expression system at a high level (72.1%) as fusion protein carrying a modified thioredoxin N-terminal region (1 21) linked to N-terminus of proinsulin by a lysine residue.
Our expectation for VCN was that, by carrying a modified C-terminus, it would display an improved affinity compared to the native molecule for integrin α5β1, a major player in angiogenesis.
To circumvent any cytotoxic immune response to β-galactosidase and allow long term transgene expression, animals received a single dose of a recombinant adenoviral vector carrying a modified CTLA4Ig as previously described.
Point mutations were introduced into the PlcR box of the plcA promoter region by PCR amplification with primer Bc-plc matching the 5' end of the plcA gene, and primers pRX1 to pRX18 carrying a modified PlcR box (supplementary Table S3).
Strains IMT5155Δyqi and IMT5155Δyqi (pDSK602 yqi), a strain carrying a modified expression plasmid with the yqi gene, that is, the complemented mutant, were tested against IMT5155, the positive control, and IMT11327, a negative control strain of avian origin lacking the gene yqi.
These strains were transformed with the vector pCT74 which carries a modified GFP sGFPP) [ 10].
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