Sentence examples for carry a defect from inspiring English sources

One attempt to track down the genetic flaw in the Belgian sufferers suggested that they could carry a defect in the same gene, but researchers dismissed the possibility because their symptoms were so different from those in people with FMF, says immunologist Seth Masters of the Walter and Eliza Hall Institute of Medical Research in Parkville, Australia, a co-author on the new paper.

All RDEB patients studied here carry a defect in the expression of COL7A1 at the protein level, but overexpress the COL7A1-specific RNA about three-fold.

Patients with this syndrome carry a defect in the genes encoding the components of the RFX complex and CIITA (Steimle et al, 1993; Villard et al, 1997; Masternak et al, 1998; Nagarajan et al, 1999).

In 1997, however, Harvard geneticists showed that the hardy worms carried a defect in a network of genes controlled by a protein similar to human insulin and IGF-1.

One of the mutants carries a defect in Sch9, which resembles two genes in the C. elegans daf-2 pathway.

When they screened the KE family to see if some carried a defect in this gene, all affected members turned out to share a specific mutation that apparently rendered FOXP2 inactive, the group reports in the 4 October issue of Nature.

By comparing tumour latency, multiplicity and type between mice with a sensitised background only versus mice also carrying a defect in an FA gene, it is possible to assess whether and how the tumour phenotype is modified.

21 In contrast to the polygenic lean GK rat model, the male ZDF rat is a diabetic model that carries a defect in the leptin receptor gene and, as a result, is hyperphagic and obese.

To test if the reduced hypocotyl elongation in dark-grown 35S ARR1 D94E seedlings is a result of increased ethylene action, we introgressed the 35S ARR1 D94E (H) line into the ethylene insensitive mutant ein2-1 that carries a defect in a key step of the ethylene response pathway [ 76].

Expression of igaA is positively regulated by Lon and negatively modulated by Hnr (MviA) through the transcriptional regulator RpoS [ 16]. S. Typhi Ty2 carries a defect in the rpoS gene [ 17, 18], which may explain the lesser degree of selection of igaA in STY.

Recent advances in the genetics of familial cancer syndromes have led to the possibility to perform genetic testing on unaffected relatives who might carry a genetic defect that predisposes them to cancer.