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A dual functionality that carries relevance for both proteasomal and autophagic degradation pathways has also been observed at the level of E3 ubiquitin ligases, with the E3 ligase CHIP being capable of generating both K48- and K63-linked ubiquitin chains.
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Based on evidence that worry is a similar process for chronic worriers and for people reporting minimal worry [31], [32], it was hypothesized that a worry induction in non-worriers would facilitate responses to threat on the dot probe task and that these findings would carry relevance for conclusions drawn from the dot probe literature in GAD patients [4], [33] and other forms of anxiety [19].
Therefore, it may carry relevance to compare mental disorders in subgroups of JSOs, especially in subgroups based on age of victim preference [ 19, 20], as well as on the number of offenders taking part in the sex offense (solo or group offenders) [ 17].
But there are also enough similarities that the British model carries special relevance.
It may be five years ago now, yet somehow the sentiment still carries some relevance even though Guardiola was right when he said Pedro would "write history here, in golden letters".
The message certainly carries contemporary relevance: The sky is as much a corporate battleground today as it was when the first billboard rose above the American highways.
Therefore, identifying individuals at risk for continuous offending carries substantial relevance, as it may enable focusing scarce resources on those most in need, i.e., by targeted use of prevention and intervention initiatives [ 8, 9].
But their views carried little relevance to life in America.
As for Mr. Fitzgerald, Mr. Safer said, whatever his popularity ratings may be now carry little relevance.
That apology carried special relevance, as the field where the Mass was held is also the site of a 1942 massacre in which a priest aligned with the Nazis led Croats in the mass killing of 2,300 Serbs, including 500 women and children.
These questions carry fresh relevance as Education Secretary Betsy DeVos continues her crusade for unrestricted school choice.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com