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The OR for GCA was 1.95 for combinations of genotypes with one or two risk alleles, whereas carriers of three or more risk alleles have an OR of 3.7.
Thus, the OR for GCA is 1.9 (CI, 1.1-2.3) for carriers of one or two risk alleles, and 3.7 (CI, 1.9-7.2) for carriers of three or more risk alleles.
One group, who genotyped 17 SNPs in the ESR1 gene, found a decreased risk of breast cancer for carriers of three common haplotypes in the gene and an increased risk for carriers of one common haplotype [ 6].
We also performed a three-polymorphism combination analysis for TOP3A rs1563634 and rs12945597, and BLM rs2532105 and found an OR = 3.8, 95% CI 2.0 7.3, for carriers of three variant alleles.
Most were heterozygous for only two conditions (4.3% of all screenees and 83.9% of multiple-disease carriers), although a small number were carriers of three (0.7 and 13.8%) or more than three conditions (0.1 and 2.3%).
Similar(55)
Diam(m)ines used in the present study belong to the carriers of six clinically approved platinum drugs.
Carriers of two 334 alleles had the lowest scores of all, averaging 45.5.
The highest score possible is 66; those without the allele scored an average of 48, whereas carriers of one copy of allele 334 scored an average of 46.3.
More than one-third of carriers of two 334 alleles said yes, compared with only 15% of those with no 334 allele.
Most individuals are actually carriers of four to six different genetic diseases, but their partner is not usually a carrier for the same genetic disease.
Carriers of one or two val alleles did not differ in their pain reports, p = 0.265.
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CEO of Professional Science Editing for Scientists @ prosciediting.com