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Ferrets receiving 244 DI virus (see below) were sedated by isoflurane inhalation before intranasal delivery of 500 μl (250 μl per nostril) of a single dose of 2 μg of 244 RNA in 300 μg of carrier virus.
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A high-pressure solution can dramatically improve the delivery of therapeutic DNA into cells, without the need for carrier viruses.
Current strategies in HCMV vaccine development imply the application of live, attenuated virus strains, DNA vectors coding for immunodominant HCMV proteins and/or genetically modified carrier viruses [31].
Delivery systems can be categorized into physical methods, conjugation methods, and natural carrier (viruses and bacteria) and nonviral carrier methods [ 8].
Designing efficient 'vectors' (antibodies, protein carriers, viruses, nanoparticles) to navigate and deliver therapeutics across the BBB in a controlled and non-invasive manner remains one of the key goals of drug development for brain diseases.
Lipid carriers, viruses and ingenious means to promote selective internalization of the RNA molecules by cellular receptors are some examples.
The Internet can be a dangerous place, with every e-mail message a potential carrier of viruses, Trojan horses or come-ons from phishers -- thieves hoping to trick you into giving up passwords, credit card numbers or other personal information.
Although EBV persists in its latent form in healthy carriers, the virus is also associated with several human cancers.
Candidates are urged not to wear neckties because they are viewed as potential carriers of viruses.
Explicit contents are the common carriers of viruses and spywares.
The Asian tiger mosquito, A. albopictus, is another prominent carrier of the virus.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com