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For the isolates typed at the RRDR locus, 98 (96.07 %) had mutated genotypes, among which 78 (76.4 % of total) carried defined targeted mutations conferring RIF resistance.
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cMAPs were engineered from a set of PTM-binding (reader) proteins and optimized using synthetic nucleosomes carrying defined PTMs.
During the past 10 years, thousands of embryonic stem cell lines and hundreds of unique animals carrying defined mutations in genes that impact on cardiac structure and/or function have been made.
Different plasmid constructs carrying defined regions upstream of the human resistin translation start site were generated in pGL3 Basic reporter plasmid (Promega) (Figure 1A).
Synthetic peptides carrying defined modifications have played important roles in a large number of studies, from use as substrates in enzyme assays to identification of protein−protein interactions.
The mod adjusts the maximum level to 35, halves the rate of increase in player experience points, reduces base player health, reduces the base weight a player can carry, defines certain characters as good or evil rather than neutral, and makes various other adjustments.
The combination of six MHC-I alleles each individual carries defines the sub-peptidome that can be effectively presented.
It is easy to implement a combinational circuit that receives as input two bits A and B (the operands) and a third bit C i (the "carry", defined in the previous stage), returning as output (1) the bit S resulting from the sum of the three input bits and (2) a new "carry" bit C o (Fig. 3).
In exchange it takes an eyebrow-raising 33% of the affiliate firm's carried interest (defined as 20% of the fund's profits).
In this paradigmatic battle between the common good and the greedy corporate elite, it would be a catastrophic failure for Americans to allow the populist mantle of a political revolution to be carried and defined by the hateful demagogue Donald Trump.
For the primary outcome measure, analyses using the per protocol (PP) sample were also carried out, defined as patients in the FA sample with no major protocol deviations.
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