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Lewnard JA, Tähtinen PA, Laine MK, et al. Impact of antimicrobial treatment for acute otitis media on carriage dynamics of penicillin-susceptible and penicillin-nonsusceptible Streptococcus pneumoniae.
In the African meningitis belt, where risk of meningococcal disease is highest, a greater understanding of meningococcal carriage dynamics is needed.
Prevalence and carriage dynamics differed by number of hours worked on the farm.
To understand SA nasal colonization and its relation with consequent disease, assessment of nasal carriage dynamics and genotypic diversity among a diverse population is a necessity.
MRSA carriage dynamics did not significantly differ by level of antimicrobial use (data not shown) or by farm type (see overlap of 95% CIs in Figure 3, panel A).
The findings of this study provides added perspective on the nasal carriage dynamics between strains colonizing persistent and intermittent carriers; an area currently in need of assessment given that persistent carriers are at greater risk of autoinfection than intermittent carriers.
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Since the dynamics of carriage within a population are complex, longitudinal carriage studies are of great value; however, few such studies have been done.
In our view, the results of this study can be valuable in terms of the competition inside the microbial community may impact nasopharyngeal dynamics and carriage of pathogenic or potential pathogenic bacteria.
It would be useful to clarify the relationship between the HIST and LIST regions to establish the dynamics of carriage of each species during the dry season in these populations.
We employed novel statistical techniques to describe the transmission and dynamics of carriage.
Few studies have been conducted that assess 1) the role of carriage prevalence in the dynamics of carriage and disease or 2) the potential effect of control programs, such as vaccination, on the transmission of meningococci.
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