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Carriage density by qPCR was determined by partial amplification of the lytA gene.
Carriage density by culture was determined as previously described, with minor modifications [ 19].
PCV also reduces the carriage density of vaccine serotypes in the nasopharynx [ 16].
Longitudinal NW samples from adults who were intranasally challenged with pneumococci were assessed for carriage density by culture and qPCR.
Several mechanisms might be responsible for the naturally acquired immune response that protects against carriage and reduces carriage density.
This is important information for future vaccine studies in which carriage density or duration may be an endpoint.
Similar(48)
Therefore, 21 of the 22 patients from Padre Cocha classified as having ACPR and parasite clearance times (PCT) of 2 3 days following treatment, had gametocyte carriage densities determined by trained laboratory personnel on days 3, 7, 14 and 28.
Treatment of malaria patients with co-artemether reduces gametocyte carriage and density in children and makes them less infectious to mosquitoes than treatment with sulfadoxine-pyrimethamine plus chloroquine (13 ).
Oral candidal carriage and relative density were not significantly associated with the other 4 parameters evaluated.
Similarly, density carriage in the HIV+ group was found to be significantly higher than in the control group (P =.0002).
Asymptomatic candidal carriage and relative density were found to be significantly higher in the oral cavity of HIV+ subjects but not associated with CD4+counts or HIV-1 RNA quantities.
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