Sentence examples for cargo exit from inspiring English sources

Cargo exit parameters, which contribute to cargo pitch after extraction, are studied.

The tER plays a key role in the formation of cargo exit sites and since the extent and amount of cargo exit sites may vary between different cell types (Fan et al. 2003; Bannykh et al. 1996) the relative content of cargo and membrane traffic proteins is expected to vary in proteomics studies using membrane-derivatives of the tER from different cell types.

It has already been reported that Exo2 blocks secretory cargo exit from the ER and disrupts the Golgi apparatus, but does not affect the morphology of the TGN [ 18].

Of note, these three post-Golgi compartments are the ones that have been best characterized for the PGCs leaving the TGN, with the total number and types of pathways for cargo exit from the TGN at present not known, although there are at least six, and probably more (Rodriguez-Boulan et al. 2005).

11) The authors may measure the exit time of the small cargo (in an experiment similar to the one presented in Figure S3b) and compare the exit of large cargo exiting Golgi through maturation.

The 'bulk flow' model proposes that soluble cargos exit the ER by default without selection (Wieland et al., 1987; Martinez-Menarguez et al., 1999; Warren and Mellman, 1999; Thor et al., 2009), and would therefore predict that alterations of overall SEC24 abundance would proportionally affect secretion of all soluble cargos.

It is important to note that the requirement for FAPP2 does not appear to be shared by all apical cargoes exiting the TGN, as Yui et al. [12] have demonstrated that constitutive transport of apical cargoes such as the Na-Cl cotransporter and the transient receptor potential vanilloid-4 is not affected in FAPP2-depleted cells.

Third, extended tracking of cargos within single pores revealed a substantial RanGTP-dependent asymmetry in the cargo's exit step.

Triad1 seems to affect either the selection of integral membrane proteins into MVBs (forcing them into a recycling mode back to the plasma membrane) or the disassembly of the sorting machinery, causing blockage of both membrane and content cargo to exit the MVB stage or fusion with the next category of lysosome-bound vesicles.

From its definition, an adaptor facilitates the cargoes to exit from the ER through protein-protein interaction.

Sar1 is the small GTPase of the COPII complex which controls transport of transmembrane and lumenal cargo via ER exit sites (Dascher and Balch 1994; Kuge et al. 1994; Aridor et al. 1995; Bonifacino and Glick 2004).