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The Center for an Urban Future recently issued a report suggesting that it made more sense economically to redevelop Aqueduct for office space and a cargo complex serving the airport.
The labor dispute that has stalled dozens of massive ships off the ports of Los Angeles and Long Beach isn't limited to the nation's busiest cargo complex.
At the ports of Los Angeles and Long Beach, the nation's busiest cargo complex, the question of whether short-haul truckers should be treated as employees has become hot, even requiring Los Angeles Mayor Eric Garcetti's intervention last year to get some drivers back to work.
This transiently gated ion-conducting channel may form pores of variable sizes up to 9 nm, which are induced by the interaction with the receptor cargo complex.
We suggest that an allosteric mechanism enhances the docking of the cargo complex to FG repeats, and thereby counteracts the repulsion of large cargoes by the permeability barrier (Ribbeck & Görlich, 2002).
Proteins that contain Nuclear Localization Signals (NLSs) are imported into the nucleus by a family of specific proteins which bind to NLS containing proteins forming a cargo complex, followed by the translocation through the NPC [ 53].
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The architecture and function of motor: cargo complexes can also be controlled by phosphorylation, calcium signaling, and proteolysis.
All Nup98 FG phases rejected inert macromolecules and yet allowed far larger NTR cargo complexes to rapidly enter.
DOI: http://dx.doi.org/10.7554/eLife.04251.017 10.7554/eLiFigure513 Figureure 13—Figure supplement 1. Partitioning of various NTR cargo complexes into TtMacNup98 FG particles.
Nuclear pore complexes (NPCs) restrict uncontrolled nucleocytoplasmic fluxes of inert macromolecules but permit facilitated translocation of nuclear transport receptors and their cargo complexes.
GLFG gels suppressed the passive influx of inert material, but also allowed a more than three orders of magnitude faster entry of NTRs and their cargo complexes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com