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The three main steps in our analysis were statistical cluster analysis of a carefully curated data set, manual exclusion of geographically isolated cells surrounded by a more biogeographically coherent cluster, and comparison of the recommended realms to previously proposed classifications (see Supplementary Table 4 in ref. 1).
Even the most powerful systems are more artistry than science, require large amounts of carefully curated data from which they still inherit significant biases, are largely unable to generalize beyond their training domain, are black boxes that even their creators don't fully understand and are for all intents and purposes little more advanced in terms of construction than the tools they replace.
For this purpose, new classifiers had to be developed which were based on carefully curated data.
The availability of large repositories of carefully curated data is critical to the progress of the field.
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In this study we present a simple bioinformatics methodology that uses public, carefully curated microarray data and the mutual information algorithm ARACNe in order to obtain a database of transcriptional interactions.
This study demonstrates that network inference using carefully curated microarray data yields reliable TRN architectures.
JNI curated data.
D.M. and A.C.L. collected and curated data.
Variations in the rate of molecular evolution were modelled by employing a nonparametric relative rate approach, that is, Tajima's relative rate test (Tajima 1993), and a phylogenetic test of the molecular clock, that is, two-cluster test (Takezaki et al. 1995), on a carefully curated CNE enhancers data set.
In the modern era we hope that carefully curated electronic medical record data can be used to more effectively define syndromic cases and mitigate this problem, but it needs to be carefully considered that in splitting we do not split apart diseases that share a substantial portion of their etiology but are misclassified due to clinical bias.
We have organized the data into carefully curated profiles for each location, industry, occupation, university, etc.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com