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Thus, it appears that careful dose modification was a successful strategy to allow further treatment in the 150 mg/m arm of this phase II trial.
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These side effects can be managed by combination therapy and/or careful dose adjustment [22, 23].
Subsequently, with careful dose adjustment and meticulous monitoring, oral As2O3 was safely administered during hemodialysis.
There was no dose modification.
No dose modification was allowed.
There was no planned dose modification.
Nobody needed to have a dose modification.
Most toxicities were manageable by dose modification.
Dose modification was specified according to toxicity.
Dose modification was used to control toxicity.
Many treatments for DSPN require careful dose titration every 2 4 weeks based on efficacy and safety.
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