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It was in 1990 that she got her big career breakthrough in Paul Verhoeven's sci-fi extravaganza Total Recall.
As far as Mr. Waltz is concerned, middle age is not a bad time for a career breakthrough.
David Ragan, in the midst of a career breakthrough, added the pole for the Brickyard 400 at Indianapolis Motor Speedway to his suddenly improved résumé.
Despite his career breakthrough playing a Baltimore villain, the 35-year-old is originally from Hackney, east London, the son of a Ghanaian mother and Sierra Leonean father.
An early career breakthrough for Sarah Jessica came in 1979, at the age of 14, when she played the lead in the Broadway production of "Annie".
The company hired her as an understudy, over the objections of the music director, Georg Solti, but in June 1963 she had a career breakthrough when she replaced an indisposed Teresa Berganza as Cherubino.
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Bale plays Rick, in the midst of a career-breakthrough into being super-hot and super-rich.
Gluck's "Orfeo ed Euridice," which Mark Morris staged as half opera, half ballet, was first broadcast in January, featuring the amazing mezzo-soprano Stephanie Blythe in a career-breakthrough performance as Orfeo.
Both records are late-career breakthroughs from artists who seemed adrift.
But as has often been the case in Dr. Janda's career, the breakthrough came on the heels of a setback: A Phase 2 clinical trial for a nicotine vaccine that was based largely on his work was declared a failure this summer when people receiving the drug quit smoking at the same rate as people receiving a placebo.
The Australian talent had only reached the cusp of what looked to be a startlingly promising career, with breakthrough performances in "Brokeback Mountain" and "The Dark Knight".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com