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Therefore, extreme care should be used when using highly negatively charged vesicles as a model system for detecting oligomer membrane permeabilization.
The acids used in the colorimetric test are caustic, therefore care should be used when performing the assay and personal protective equipment such as gloves and safety glasses are essential.
However, as shown by our study and in vitro experiments (Ma et al., 2011; Knollmann, 2013), it is also an important indicator of the fact that the cells the Paci2013 model is based on, and more in general hiPSC-CMs, were not behaving exactly like adult cells, thus particular care should be used when considering them as fully representative models of adult cells.
Pearls are easily damaged and extreme care should be used when cleaning them.
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The study emphasized that institutional care should be used only when strictly necessary as an existing body of knowledge shows – among others - that for every three months spent within such an institution, a child's physical development was delayed by one month.
4 The British National Clinical Practice Guidelines on management of depression in primary and secondary care 19 recommend that ultrashort tests should only be used when there are sufficient resources for second-stage assessment of those who screen positive.
With TRICKS, k-space data are shared between successive data sets, which leads to minor temporal interpolation artefacts thus, TRICKS data should be used with care when a rapid signal change is observed (as, for example, during bolus arrival) (Fig. 8).
In summary, our data validate the use of these antibodies for immunoblotting but suggest that they should be used with care when used for immunocytochemistry.
Therefore, although the Poisson assumption generates estimates of adult mortality that are essentially identical to those produced using the data, it should be used with care when modeling to assess population viability and fluctuations.
This phenomenon has already been observed in a cross-sectional design and suggests that full likelihood-based beta regression methods should be used with care when analyzing HRQL [ 3].
Our findings suggest that these methods should be used with care, especially when the genetic variance is very small, so that predictive accuracy is likely to be either inestimable or overestimated.
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CEO of Professional Science Editing for Scientists @ prosciediting.com