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We thank all nurses and physicians of the intensive care unit who have excellently assisted the study team with screening, randomization and clinical care of study patients.
We acknowledge the support received from the NARI institutional staff and the project staff of the PAVE, HIVNET and Acute Pathogenesis studies for counseling, clinical care of study participants, community work, laboratory work, data management, and statistical support from National AIDS Research Institute, Pune and Johns Hopkins University, Baltimore.
This tended to dilute the potential impact of their work on the care of study patients.
HEW planned the study, wrote the study protocol, took care of study patients, and performed the analysis of the data.
On a regular basis, we contacted health professionals involved in the ambulatory care of study participants in order to resolve perceived gaps or inconsistencies in collected information.
The research team was distinct from the clinical team – none of the researchers were involved in the clinical care of study participants.
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Care of studied animals was in accordance with National Institutes of Health guidelines.
Structured non-participant observations of the experience of care on study wards were undertaken by using dementia care mapping.
Care providers of study children were requested to complete the risk assessment form with assistance provided as needed.
The average duration of SDD/SOD use per ICU was 7.05 years (range 6.8 to 7.5 years), excluding the 6-month standard care period of study period I.
Contamination between study arms might have occurred, due to the fact that the same physician took care of both study groups.
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