Sentence examples for cardiac force from inspiring English sources

This implies that modulation of the Ca2+ spark rate may control the Ca2+ transient amplitude and cardiac force development (inotropy).

Since ∆[Ca2+]i is an important mediator of cardiac force development, a decreased ∆[Ca2+]i due to decreased SR load may result in decreased force development.

LPS impaired phospholamban phosphorylation, cardiac force-frequency relationship and FDAR.

First, we tested whether LPS would reduce phospholamban phosphorylation and disrupt cardiac force-frequency relationship and FDAR.

The frequency-dependent acceleration of relaxation is one of the physiological mechanisms to maintain adequate ventricular filling at increased heart rates, and therefore Joulin and colleagues tested the hypothesis of whether endotoxin (lipopoly-saccharide) may impair the cardiac force-frequency relationship [ 3].

With a transient or chronic reduction of blood flow to the heart, cardiac muscle force production is impaired regardless of ATP or Ca2+ availability, suggesting that the depression of force is produced in part by intrinsic changes to the contractile filaments [8] [14].

These drugs increase the level of calcium by inhibiting the Na+/K+-ATPase, and thereby increase cardiac contractile force.

Omecamtive mecarbil (OM) is known to specifically target βMys and upregulate cardiomyocyte contractile displacement and cardiac contractile force.

In general, we found that expression of cardiac structural and force generating protein genes in the FH cells was not significantly higher than in the CM populations.

Ventricular myosin (βMys) is the motor protein in cardiac muscle generating force using ATP hydrolysis free energy to translate actin.

Muscarinic receptors are stimulated by the postganglionic cholinergic neurons of either the parasympathetic or the sympathetic cholinergic systems that mediate smooth muscle relaxation, glandular secretion, and modulation of cardiac rate and force [ 38].