Sentence examples for card domain from inspiring English sources

The CARD domain of ASC then binds the CARD of caspase-1 via CARD-CARD interaction serving as a bridge between pro-caspase-1 and pyrin-containing inflammasomes21.

The apical caspase caspase 9 is activated by homodimerization through its CARD domain.

Whether ASC is also required to NLR family, CARD domain containing 4 (NLRC4) inflammasome activation is less clear5.

The exposed CARD of RIG-I or MDA5 interacts with the CARD domain of the mitochondrial antiviral adaptor protein (MAVS 18.

However, unlike NLRP3 and AIM2, NLRC4 contains its own CARD domain, which can interact directly with capase-1, thus making ASC dispensable for NLRC4-dependent caspase-1 activation2.

First, we showed that caspase 9 could be activated by a two-protein format with replacement of the CARD domain with both FRB and FKBP12.

Assembly of the MAVS filament is mediated by its CARD domain (CARDMAVS), and requires its interaction with the tandem CARDs of RIG-I (2CARDRIG-I).

This interaction is dependent on the N-terminal CARD domain of MAVS.

These data suggested that REUL ubiquitinates the CARD domain of RIG-I.

Both of them deliver ubiquitin to the CARD domain of RIG-I.

Other examples are the untypical secondary structure prediction for the CARD domain of Ipaf, or the partial sequence of the type 1 isoform of CIITA (accession number: AF000002) [21], which contains an alternative 5' region that encodes a CARD domain.