Sentence examples for carcinoma microenvironment from inspiring English sources

Decreased number and impaired function of dendritic cells (DCs) have been found in ovarian carcinoma microenvironment.

The contribution of the unique ovarian carcinoma microenvironment to the development and progression of metastatic disease is an area of active investigation.

The single-cell-cloned CSCs treated with the different tumor cell/tissue-derived conditioned culture medium, which is a mimic of carcinoma microenvironment, could differentiate into corresponding tumor cells and express specific markers of the respective type of tumor cells at the gene, protein and cell levels, respectively.

Interestingly, this multilineage differentiation potential of single-cell-cloned liver CSCs sharply declined after the specific knockdown of octamer-binding transcription factor 4 (Oct4) alone, even though they were under the same induction conditions (carcinoma microenvironments).

Also, the lab's goal is to define immune surveillance and escape mechanisms present in the human cutaneous squamous cell carcinoma (SCC) microenvironment to ultimately identify novel targets for immunotherapy.

We paid particular attention to the source of CSCs and possible regulatory pathway in nasopharyngeal carcinoma (NPC) microenvironment herein.

Various types and stages of tumor vasculature in murine mammary carcinoma at the microenvironment level have previously been characterized morphologically and compared to normal vasculature by the visual inspection of IVM images (Boucher et al. 1996).

The potential therapeutic use of TSA should take into account the variable aggressiveness of breast carcinoma cells and microenvironment signals such as HGF at the secondary growth site of the tumour.

EMT could be a reversible, dynamic process and may be regulated by the tumour microenvironment, carcinoma cells that have undergone EMT during invasion seem to regain their epithelial characteristics at the metastatic sites [ 24].

As the carcinoma progresses, the microenvironment of cancer cells coevolves into an activated status through continuous paracrine communication and the concurrent activity of stromal and cancer cells, thus creating a dynamic signaling circuitry in which diverse molecules cooperate to promote tumor expansion and invasiveness, ultimately leading to the development of a fatal disease [ 4].

In the tumor microenvironment, carcinoma-associated fibroblasts (CAFs) represent a fibroblast population or mixture of sub-populations that can promote tumor progression [ 8– 13].