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New central cores with carbon side chains were explored to improve potency.
The carbon side is modeled by graphene sheets with either zigzag or armchair termination.
The Energy Bill settlement between the energy secretary and the chancellor is a battle won for the low carbon side, since it will unlock investment in renewables to 2020 and make a decarbonisation target for electricity politically inevitable.
I think that if you read the tea leaves here, the president has kicked this argument up and away from the jobs argument and put it down on the carbon side of the discussion, and that is probably ultimately favourable to environmentalists.
The grids were put on the surface of Matrigel matrix with the carbon side on the top.
It seemed that the cytotoxicity decreased with increased in the length of the carbon side chain or introduction of a polar functionality at this location [52].
Similar(41)
CHEBI:58955 branched-chain fatty acid anion Any fatty acid anion with a carbon side-chain or isopropyl termination.
However, the length of the carbon side-chain was important, suggesting necessity of solubilisation of the lysophospholipid in the lipid bilayer.
Selected compounds with a short side chain (7DHP, pD, pL, 20(OH)7DHP, 20(OH pD) were also tested against leukemia cells in comparison to vitamin D3 hydroxy-derivatives with a full 8 carbon side-chain.
The alkylphenols are a structurally related (and therefore interesting to compare mechanistically) set of such compounds; they vary in their carbon side-chain length or, in the case of bisphenol A (BPA), have a phenol group instead of an alkyl side chain [see Supplemental Material (doi 10.1289/ehp.1002512)].
Specifically, phthalates with four to six carbon side-chains interfere with testosterone production by inhibiting cholesterol uptake into the mitochondria by steroidogenic acute regulatory protein and by inhibiting some, but not all, of the enzymes in the steroidogenic pathway (Barlow et al. 2003).
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