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Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain.
Removal of the N-glycosylated carbohydrate chain at the Cυ3 domain by substituting an N408 residue for alanine also resulted in lowered qIgY-Fc uptake.
The artificial systems consist of a carbohydrate chain containing some 5-20 andms and in one end a molecule that associates easily with water.
The possibility of the direct synthesis of tetroses, keto- and aldo-pentoses from pure formaldehyde due to the combination of the photochemical production of glycolahyde and phosphate-catalyzed carbohydrate chain growth is demonstrated.
This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.
These derivatives included NM385 (no detectable receptor binding activity), hyperglycosylated analogs with different carbohydrate contents and receptor binding activities; (NM294: +1 carbohydrate chain; darbepoetin alfa: +2 carbohydrate chains) and polyethylene glycol (PEG) derivatives (PEG-darbepoetin alfa, PEG-rHuEPO and PEG-NM385).
Similar(29)
The difference in isoelectric points was shown to be due to microheterogeneity of the carbohydrate chains.
Their carbohydrate chains were unprecedented and have never been found in oligosaccharides from other biological sources, except Erylus spp. Three carbohydrate chains in the glycosides 3 and 6, 4 and 7, 5 and 8 correspondingly are new.
It has also been confirmed that this enzyme catalyzed cleavage of sulfate in the C-4 position of xylose incorporated into carbohydrate chains of saponins from sea cucumbers81.
Mass spectrometry of chemically deacylated LAM indicates the presence of LAM-specific carbohydrate chains, which maintain antigenicity in immunoassays.
Consequently, this carbohydrate/electron-transfer peptide could be a powerful tool for cell sensing and searching for carbohydrate chains on a cell surface.
More suggestions(15)
glucose chain
hydrocarbon chain
carbohydrate process
carbohydrate link
carbohydrate structure
carbohydrate data
carbohydrate channels
carbohydrate strings
carbohydrate content
carbohydrate metabolism
carbohydrate recognition
carbohydrate intake
carbohydrate absorption
carbohydrate information
carbohydrate analysis
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