Sentence examples for car formation from inspiring English sources
Thus, these results demonstrate that Chk1 haploinsufficiency may result in improper CAR formation, presumably leading to unsuccessful enculeation during erythropoiesis.
Furthermore, these Chk1+/− erythroid progenitors exhibited a marked increase in spontaneous DNA damage foci and aberrant CAR formation during RBC differentiation.
Interestingly, we observed aberrant CAR formation in the Chk1+/− erythroid cells at stage IV as compared to the CAR observed at stage IV in WT erythroid cells.
Future studies will be required to determine if interactions between Chk1 and the recently identified adaptor protein mDia2 during CAR formation play any role in enucleation during erythropoiesis.
Our results indicate that improper CAR formation in Chk1+/− erythroid cells during late stages of erythropoiesis, provides one of the explanations for unsuccessful enucleation.
These experiments demonstrated the consequences of failing to properly regulate actin filaments necessary for contractile actin ring (CAR) formation, which is required for erythroblast enucleation to generate mature RBCs [8].
From 1906 the standard formation was six cars, with an equal number of motor and trailer cars running in either two or four car formations off-peak.
Initially run in seven-car formations, they have now been lengthened to eight cars.
They were delivered in six-car formations (the 6Bs including a buffet car) and two units were often operated in multiple to form twelve-car trains.
It had been intended to operate the new trains with four or six cars, but after initial problems with the traction current only six-car formations were used.
