Results from this study indicate that BayesB and SPLS capture the linkage disequilibrium between markers and traits effectively leading to higher accuracies.
Although nflank is defined as a parameter to capture the linkage disequilibrium among the top SNPs and their flanking SNPs, the contribution of linkage disequilibrium to additive variance is not considered in this approach (Gianola et al. 2009).
One unique feature of the Archimedes Model is that it spans multiple diseases and captures the linkages between diseases and disease outcomes.
We have previously shown that tagging SNPs capturing the linkage structure defined by physical position 88,901,306 to 88,916,775 are adequate to resolve an association with obesity-related dylipidemia [4].
Aiming to better utilize the GWAS data, we also captured the linkage disequilibrium (LD) blocks of each tagSNP for different populations, which was defined as the GWAS identified trait associated regions.
In particular, CGE models are abstraction, complex and are able to capture the inter-linkages between different sectors in the economy as well as between different economies (Kehoe and Kehoe (1994)).
This research highlights the utility of diary methodology to test whether questionnaires capture the specific situation-behavior linkages they are designed to measure.
To capture the production and consumption linkages, taking into account the supply rigidities present in Pakistan, we use a semi-input output model with consemi-input outputelationships amodelquantities in the model and fixed prices.
The limitation of our study is that the linkage may capture the signal from the potential co-inheritance of genetic variants linked to another phenotype and to the underlying T2D that is commonly shared with hypertension; however, as T2D patients have high prevalence of hypertension, virtually all linkage studies performed in T2D may as well mask a linkage with hypertension.
Fifth, our model and dataset do not have the linkages to fully capture the impact of increased protection for IP.
