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Results from this study indicate that BayesB and SPLS capture the linkage disequilibrium between markers and traits effectively leading to higher accuracies.
Although nflank is defined as a parameter to capture the linkage disequilibrium among the top SNPs and their flanking SNPs, the contribution of linkage disequilibrium to additive variance is not considered in this approach (Gianola et al. 2009).
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Most importantly, the present work showed that the estimated inventories are able to capture the linkages with the physical oceanic features of the system and we propose this method as an inexpensive solution to support the design of monitoring activities in the Mediterranean Sea, which is still poorly constrained by direct observations.
We have previously shown that tagging SNPs capturing the linkage structure defined by physical position 88,901,306 to 88,916,775 are adequate to resolve an association with obesity-related dylipidemia [4].
Aiming to better utilize the GWAS data, we also captured the linkage disequilibrium (LD) blocks of each tagSNP for different populations, which was defined as the GWAS identified trait associated regions.
One unique feature of the Archimedes Model is that it spans multiple diseases and captures the linkages between diseases and disease outcomes.
In particular, CGE models are abstraction, complex and are able to capture the inter-linkages between different sectors in the economy as well as between different economies (Kehoe and Kehoe (1994)).
The spectrum of PMTCT services may thus encompass several physical locations within one facility, or incorporate different facilities, adding to the complexity of data capture and linkage throughout the service continuum.
The limitation of our study is that the linkage may capture the signal from the potential co-inheritance of genetic variants linked to another phenotype and to the underlying T2D that is commonly shared with hypertension; however, as T2D patients have high prevalence of hypertension, virtually all linkage studies performed in T2D may as well mask a linkage with hypertension.
We will argue that they capture the information provided by linkage measures but they also provide additional information related to the diffusion properties.
These involve thousands and for some species hundreds of thousands of SNPs approximately equally spaced across the genome, to capture the greatest amount of linkage disequilibrium with causative QTL.
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