Sentence examples for capture sequencing from inspiring English sources

Interestingly, circularized chromosome conformation capture sequencing (4C-seq) shows that poised enhancers already establish physical interactions with their target genes in ESCs in a polycomb repressive complex 2 (PRC2 -dependent manner.

Deep sequencing of the genome of 53BP1−/− cancer cells and translocation capture sequencing (TC-Seq) of primary 53BP1−/− B cells revealed that their chromosomal rearrangements differ from those found in wild-type cells in that they show increased DNA end resection.

Targeted DNA Sequence Capture Sequencing.

Whole-exome capture, sequencing, and bioinformatic analysis were performed as reported.

DNA was processed for exon capture sequencing according to established protocols [ 10].

Our pooling approach saved over $39,350 compared to an unpooled, targeted capture sequencing strategy.

By Sanger sequencing we also confirmed the CHD-specific rare mutation RCAN1.4E25K identified from target-capture sequencing (Fig. 1F).

The −2 kb of 5′-upstream regulatory regions, coding regions and 3′UTRs for RCAN1.1 and RCAN1.4 transcripts were first sequenced by target-capture sequencing in 412 blood samples of sporadic CHD patients and 213 matched controls from Shandong populations (Table S1).

DNAm profiles were analyzed by methyl-capture sequencing (MethylCap-seq), which is based on precipitation of methylated DNA by recombinant methyl-CpG binding domain of MeCP2 protein.

It is therefore of great interest that mtDNA sequences have been resolved through off-capture sequencing using conventional whole-exome sequence (WES) methods.

We also performed cDNA-capture sequencing 8 for 5463 cancer-related genes, with the cDNAs of these genes being enriched with the use of custom-made capture probes.