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We also hypothesize that matrix production is not capsule-dependent because it has been shown that rough strains are still capable of forming a sticky matrix in a biofilm assay [6].
Here, we could demonstrate that these bacteria specifically invade PCPEC from the basolateral side in a capsule-dependent manner [ 7].
These experimental results demonstrate that immunomodulation by H. influenzae can dictate the relative capsule-type-dependent fitness of pneumococcal strains.
Finally, the increase in capsule size is dependent on the organ of infection, with capsules being larger in the lung than in the brain (16).
Consisting of little more than strands of DNA or RNA stuffed into a protein capsule, they are entirely dependent on their host for survival and replication.
On the contrary, capsule morphology is considerably dependent on the amount of shell components for a given oil-to-water ratio.
As observed from experiments, the capsule material exhibits time-dependent characteristics.
Killing in this assay was dependent on the capsule type rather than genetic background.
However, capsule production in GAS is dependent only upon functional hasA and hasB, but not hasC [ 66].
For an invasive serotype like serotype 5, it also shows that the ability of an isolate to cause invasive disease is not only dependent on the capsule type but also the genetic background of the strain.
The success of these vaccines reflects their ability to induce a functional antibody response directed at the bacterial capsule that is T-cell dependent, resulting not only in a robust initial response but also in the establishment of immunological memory [ 2].
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