Sentence examples for capacity trial from inspiring English sources

Exact(1)

Last month, a Los Angeles judge halted the mental capacity trial after one day when the ailing mogul testified, by using profanities, that he wanted Herzer out of his life.

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The CAPACITY trials (studies 004 and 006) [ 1] evaluated the efficacy and safety of treatment with pirfenidone for a minimum of 72 weeks; the ASCEND trial (study 016) [ 2] evaluated treatment with pirfenidone for 52 weeks.

In a prespecified mortality analysis combining the 1-year results from both the ASCEND trial and the previously reported CAPACITY trials, there was evidence that pirfenidone reduced mortality in IPF patients.

In a prespecified analysis combining results from the ASCEND and CAPACITY trials, all-cause death at 1 year was significantly reduced from 6.7% in the placebo group to 3.5% in the pirfenidone group.

Evaluation of outcomes in the CAPACITY trials showed that pirfenidone significantly reduced the decline in FVC % pred at week 72 in study 004, but not in study 006 [ 1], prompting a third multinational phase 3 trial (ASCEND) to confirm the effect of pirfenidone in patients with IPF.

Briefly, however, it appears from the presented data that pirfenidone treatment resulted in a significant reduction in FVC decline compared with placebo in the CAPACITY 2 trial at 72 weeks, although no such significance was reached in the CAPACITY 1 trial.

The CAPACITY 2 trial, using a lower dose of pirfenidone, reached its primary endpoint [ 57].

GP research capacity and trial participation; Table  4: Most GP staff reported that their capacity to participate in research was constrained because of time limitations.

GP research capacity and trial participation: GP staff considered the design increased generalisability, as staff who would not normally volunteer to participate in research due to perceived time constraints and paperwork might do so.

Those who lack capacity in trials with complex designs should be afforded the same care in relation to consent as competent adults in trials with simpler designs.

Rather, sites with clinical trial capacity should endeavour to share resources (skills, laboratory capacity, community engagement efforts) to reduce the opportunity costs of a single trial with a long-term developmental agenda in mind.

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