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Moreover, supporting this physiological capacity implantation of 8 weeks old hESC-NPs into the neural tube of chick embryos also produced human neurons expressing specific PNS markers in vivo in just a few days.
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However, the method we used to treat metastatic melanoma with CONPs, systemic therapy, may tend to weaken the implantation capacity of circulating tumor cells in the lung.
Furthermore, the cellular responses of canine bone marrow stromal cells (cBMSCs) and bone formation capacity after the implantation of Mg/CSH in tibia defects of canine were investigated.
Nevertheless, recent studies on cryodamaged 4-cell stage embryos showed that the loss of one blastomere (25%) does not affect the embryo's implantation capacity (Edgar et al., 2007).
Altogether, our results indicate that the proangiogenic capacity of implanted periosteal cells is HIF-1α regulated and that metabolic adaptations mediate post-implantation cell survival.
Consistent with this, others have had difficulties to maintain or expand ES cells isolated from mammalian iNT embryos in vitro,, and observed reduced implantation capacities of cybrid cells in in vivo transplantation experiments in fish.
Low osteogenic capacity of the ectopic implantation site as well as missing osteoinductive properties of the scaffold must be assumed as possible reasons for our results [ 15].
In bone tissue engineering, no reliable markers have been identified which are able to predict the bone-forming capacity of hMSCs prior to implantation.
Previous studies have shown that rat aortic valve grafts exhibit synthesis of procollagen, suggesting a capacity for repair and regeneration after implantation.
This indicates that the osseointegration capacity of the unmodified PEEK implant was very limited, even when the implantation period was extended.
Expression of CD31 in implanted LSCC blood vessels) and Ki67 in its epithelial cells and 2(f)) indicated that the implanted tissue retained features of the original tumor and preserved proliferative capacity even after 96 hours after the implantation.
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