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The design of synthetic proteins holds the potential to exploit their functional capacity for novel purposes, although much work remains to achieve a complete understanding of protein folding.
Equally important, as science expands into new territory – CAR-T, CRISPR, RNA therapeutics, gene therapy, etc. – the translational challenges faced by drug developers have never been experienced before, and their solutions require ingenuity and a capacity for novel thinking, abilities that do not correlate with scale either.
MeSHOP comparisons are demonstrated to provide predictive capacity for novel relationships between genes and human diseases.
This ability to change functional macrocircuitry of the brain through changes in gene expression in a single neuroblast reveals a surprising capacity for novel circuit formation in the brain and provides a paradigm for large-scale evolutionary modification of circuitry.
In addition, a GGAGG-containing element suggests further capacity for novel structure formation; these elements can form stable stacked structures of GGAGGA hexads and GGGG tetrads, and can do so in trans.
The information obtained in the key informant interviews is summarized in this section by the main topics: disease investigation and surge capacity, use of the Incident Command System (ICS) to manage the public health response, epidemiologic data sources for situation awareness, laboratory capacity for novel influenza A (H1N1) testing, and regional communication.
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A person's capacity for novel-writing and the kinds of thing a novelist writes are surely no more complex or mysterious than a tendency towards jealousy or a reluctance to hug one's siblings.
The calculated shear capacity agrees well with experimental and numerical ones, indicating provided analytical equations can accurately predict shear capacity for such novel joint structure.
Therefore, as in the case shown by earlier studies [13], SVM has certain capacity for identifying novel active compounds from sparse as well as regular-sized active datasets.
We describe a sentinel surveillance system that could enhance the quality of influenza epidemiologic and laboratory data and strengthen a country's capacity for seasonal, novel, and pandemic influenza detection and prevention.
The retention and capacity for generation of novel adaptive genetic variation in a population is key to conservation efforts.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com