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In a more recent study, the same group demonstrated that mitochondrial biogenesis is capable to restore oxidative metabolism in an experimental model of murine peritonitis, thus providing a potential mechanism affecting sepsis outcome [129].
Intense research is conducted to identify microRNAs susceptible to be used as biomarkers and to design new therapeutic approaches based upon using synthetic microRNA mimics and inhibitors as well as finding new drugs capable to restore or modify microRNA expression in the context of gut pathologies.
Moreover, the antioxidant actions of extra virgin OO components such as tyrosol are capable to restore the intracellular antioxidant defences [59] decreased among depressive patients.
More importantly, the addition of the BMP antagonist Noggin was capable to restore the high levels of co-stimulatory molecule expression when DCs were co-cultured with NPCs and the BMP-secreting [33] ATDcondrogenicnic precursor cells only (Figure 8A C).
Thiazolidinediones, which are capable to restore glucose utilization, have recently been shown to favorably modify diastolic function as evident from improvement the in E'septal velocity [ 51].
However, even if anti-Nanog siRNA transfections are capable to restore Brachyury expression, they do not restore skeletal myogenesis of p53−/− ESCs.
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"Surely, I thought, if man can take the ruins, rubble, and remains of a broken city and rebuild an awe-inspiring structure that rises toward the heavens, how much more capable is our Almighty Father to restore His children who have fallen, struggled, or become lost?" No matter how ruined our lives may seem, President Uchtdorf declared that God regards all His children as "worthy of rescue".
Pim inhibitors are capable of counteracting these effects to restore osteoblastogenesis.
He seeks to restore a feisty spirit, capable of recapturing consumers lost to surging competitors.
In contrast to the Y750W mutant, which is still capable to bind myosin and restore muscle function, the N758Y and Δ602 630 mutants neither rescue the defect in sarcomere organization nor bind to UNC-54 in immunoprecipitation experiments.
As a result, there is a significant clinical need to develop materials capable of restoring function to the meniscus following an injury.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com